GRANIFER – Granisetron Injection IP 3 mg
Product Overview
GRANIFER (Granisetron Injection IP 3 mg) is a selective 5-HT3 (serotonin) receptor antagonist indicated for the prevention and treatment of nausea and vomiting associated with chemotherapy, radiotherapy, and postoperative recovery.
Granisetron works by blocking serotonin receptors responsible for triggering the vomiting reflex, helping patients remain comfortable during cancer treatment and after surgical procedures.
GRANIFER is intended for administration by qualified healthcare professionals in hospitals, oncology centers, and clinical settings.
| Attribute | Details |
|---|---|
| Brand Name | GRANIFER |
| Generic Name | Granisetron Injection IP |
| Strength | 3 mg |
| Dosage Form | Injection |
| Pack Size | 3 ml Vial |
| Therapeutic Category | Antiemetic |
| Route of Administration | Intravenous (IV) |
| Manufacturer | Pharmafer Pvt. Ltd. |
| Storage | Store below 30°C. Protect from light. Do not freeze. |
Uses of GRANIFER
Key Uses
- Prevention of chemotherapy-induced nausea and vomiting (CINV)
- Prevention of radiation-induced nausea and vomiting (RINV)
- Prevention and treatment of postoperative nausea and vomiting (PONV)
- Supportive care in oncology treatment protocols
Benefits
Why Choose GRANIFER?
Rapid Onset of Action
Provides effective prevention of nausea and vomiting during chemotherapy and surgical procedures.
Proven Antiemetic Therapy
Granisetron is a well-established 5-HT3 receptor antagonist with demonstrated clinical effectiveness.
Improves Patient Comfort
Helps patients tolerate chemotherapy and postoperative recovery more comfortably.
Long-lasting Relief
Provides sustained control of nausea and vomiting during high-risk treatment periods.
Hospital and Oncology Use
Suitable for use in oncology departments, surgical units, and healthcare institutions under medical supervision.
Mechanism of Action
Granisetron selectively blocks 5-HT3 (serotonin) receptors located in both the gastrointestinal tract and the central nervous system.
During chemotherapy or radiotherapy, damaged cells release serotonin, which activates these receptors and triggers nausea and vomiting. By blocking this pathway, GRANIFER helps prevent these symptoms.
Administration
- To be administered only by a qualified healthcare professional.
- Dosage should be determined by the treating physician based on the patient’s condition and treatment protocol.
- Not intended for self-administration.
Possible Side Effects
Like all medicines, GRANIFER may cause side effects, although not everyone experiences them.
Common side effects may include:
- Headache
- Constipation
- Diarrhea
- Weakness
- Injection site discomfort
- Dizziness
Patients should consult their healthcare provider if symptoms persist or worsen.
Precautions
- Use only under medical supervision.
- Inform your physician about any history of heart rhythm disorders.
- Use with caution in patients with liver impairment.
- Inform your doctor about all current medications before treatment.
- Pregnancy and breastfeeding: Use only if prescribed by a healthcare professional.
Frequently Asked Questions
GRANIFER is used to prevent and treat nausea and vomiting caused by chemotherapy, radiotherapy, or surgical procedures.
It blocks serotonin (5-HT3) receptors that trigger the vomiting reflex, helping prevent nausea and vomiting.
GRANIFER should only be administered by qualified doctors, nurses, or trained healthcare professionals.
Yes. It is commonly used to prevent postoperative nausea and vomiting as directed by the treating physician.
Yes. It is indicated for preventing chemotherapy-induced nausea and vomiting as part of supportive cancer care.
