Birafer – Abiraterone Acetate Tablets 250 mg
Product Overview
BIRAFER (Abiraterone Acetate Tablets 250 mg) is an oral anticancer medicine indicated for the treatment of advanced prostate cancer in adult men. It belongs to the class of androgen biosynthesis inhibitors, which reduce the production of testosterone, a hormone that promotes the growth of prostate cancer cells.
BIRAFER is prescribed in combination with prednisone or prednisolone as part of standard treatment protocols and should only be used under the supervision of an oncologist or qualified healthcare professional.
| Attribute | Details |
|---|---|
| Brand Name | BIRAFER |
| Generic Name | Abiraterone Acetate Tablets |
| Strength | 250 mg |
| Dosage Form | Film-Coated Tablets |
| Packaging | Bottle of 120 Tablets |
| Therapeutic Category | Anticancer / Androgen Biosynthesis Inhibitor |
| Route of Administration | Oral |
| Manufacturer | Pharmafer Pvt. Ltd. |
| Storage | Store below 30°C in a cool, dry place. Protect from moisture and direct sunlight. |
Uses of Birafer
BIRAFER is indicated for:
- Metastatic castration-resistant prostate cancer (mCRPC)
- Metastatic hormone-sensitive prostate cancer (mHSPC)
- Treatment in combination with prednisone or prednisolone as prescribed by an oncologist
- Long-term hormonal therapy for eligible prostate cancer patients
Benefits
Suppresses Androgen Production
Inhibits the CYP17 enzyme responsible for testosterone production, helping slow the growth of prostate cancer cells.
Proven Hormonal Therapy
A well-established treatment option used worldwide in advanced prostate cancer management.
Convenient Oral Administration
Film-coated tablets provide an effective oral treatment option as part of long-term therapy.
Supports Comprehensive Cancer Care
Used in combination with corticosteroid therapy according to established oncology treatment guidelines.
Trusted Oncology Medicine
Manufactured to high pharmaceutical quality standards to support healthcare professionals in cancer treatment.
Possible Side Effects
Like all medicines, BIRAFER may cause side effects, although not everyone experiences them.
Common side effects may include:
- Fatigue
- Nausea
- Joint pain
- Muscle weakness
- Fluid retention or swelling
- High blood pressure
- Low potassium levels
- Hot flushes
- Elevated liver enzymes
Patients should immediately report symptoms such as jaundice, severe weakness, chest pain, or difficulty breathing to their healthcare provider.
Mechanism of Action
Abiraterone Acetate selectively inhibits the CYP17 (17α-hydroxylase/C17,20-lyase) enzyme involved in androgen biosynthesis. This significantly reduces testosterone production from the testes, adrenal glands, and tumour tissue. Since prostate cancer cells often rely on androgens for growth, lowering hormone levels helps slow disease progression.
Dosage & Administration
- Take only as prescribed by your oncologist.
- Usually administered together with prednisone or prednisolone.
- Swallow tablets whole with water.
- Take on an empty stomach, at least 1 hour before or 2 hours after food.
- Do not crush, chew, or break the tablets.
Frequently Asked Questions
BIRAFER is used in the treatment of advanced prostate cancer in adult men as prescribed by an oncologist.
It reduces testosterone production by inhibiting the CYP17 enzyme, helping slow the growth of prostate cancer cells.
No. BIRAFER should be taken on an empty stomach, at least one hour before or two hours after meals.
No. BIRAFER is a hormonal therapy (androgen biosynthesis inhibitor) and not a chemotherapy medicine.
Yes. Your doctor may monitor liver function, blood pressure, potassium levels, and treatment response throughout therapy.
